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Anti-Alpha Actinin 2 Antibody (2O342) 是一种 Rabbit 抗体,靶向 Alpha Actinin 2。Anti-Alpha Actinin 2 Antibody (2O342) 可用于 WB,IHC,IP。
Anti-Alpha Actinin 2 Antibody (2O342) 是一种 Rabbit 抗体,靶向 Alpha Actinin 2。Anti-Alpha Actinin 2 Antibody (2O342) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Alpha Actinin 2 Antibody (2O342) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (2O342) can be used in WB,IHC,IP. |
别名 | sm Actinin-alpha, F-Actin Cross-Linking Protein, CMD1AA, alpha-SCA, alpha-actinin-2, alpha actinin skeletal muscle isoform 2, alpha actinin skeletal muscle, alpha actinin 2, ACTN2, ACTN 2, Actinin alpha 2, Actin binding protein |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of ACTN2 on human heart lysates using anti-ACTN2 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse skeletal tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 104 kDa. |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
运输方式 | Shipping with blue ice. |
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