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Anti-APOE Monoclonal Antibody (2O907) 是一种 Mouse 抗体,靶向 APOE。Anti-APOE Monoclonal Antibody (2O907) 可用于 IHC,FCM。
别名 MGC1571, LPG, LDLCQ5, AD2
Anti-APOE Monoclonal Antibody (2O907) 是一种 Mouse 抗体,靶向 APOE。Anti-APOE Monoclonal Antibody (2O907) 可用于 IHC,FCM。

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| 产品描述 | Anti-APOE Monoclonal Antibody (2O907) is a Mouse antibody targeting APOE. Anti-APOE Monoclonal Antibody (2O907) can be used in IHC,FCM. |
| 别名 | MGC1571, LPG, LDLCQ5, AD2 |
| Ig Type | IgG1 |
| 克隆号 | 2O907 |
| 反应种属 | Human |
| 应用 | IHCFCM |
| 推荐剂量 | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Tissue specificity: Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human ApoE expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | APOE |
| 基因ID | |
| 蛋白名称 | Apolipoprotein E |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |