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ULBP-2 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00136

别名 ULBP-2/5/6, ULBP2, RAET1L, RAET1H, NKG2DL2, NKG2D ligand 2, N2DL2, ALCAN-α, ALCAN-alpha

ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

ULBP-2 Protein, Human, Recombinant (His & Avi)

ULBP-2 Protein, Human, Recombinant (His & Avi)

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Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00136 别名 ULBP-2/5/6, ULBP2, RAET1L, RAET1H, NKG2DL2, NKG2D ligand 2, N2DL2, ALCAN-α, ALCAN-alpha

ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

规格价格库存数量
5 μg
¥ 246
6-8日内发货
10 μg
¥ 383
6-8日内发货
20 μg
¥ 616
5日内发货
50 μg
¥ 1,190
5日内发货
100 μg
¥ 1,990
5日内发货
200 μg
¥ 3,590
5日内发货
500 μg
¥ 8,000
5日内发货
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产品介绍


生物活性
产品描述
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
生物活性
Immobilized Human ULBP-2, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 2.8μg/ml determined by ELISA.
研究背景
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q9BZM5
蛋白构建Gly26-Ser217
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名ULBP-2/5/6, ULBP2, RAET1L, RAET1H, NKG2DL2, NKG2D ligand 2, N2DL2, ALCAN-α, ALCAN-alpha
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量24.6 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

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