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Anti-GCNT1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GCNT1。Anti-GCNT1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-GCNT1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GCNT1。Anti-GCNT1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-GCNT1 Polyclonal Antibody is a Rabbit antibody targeting GCNT1. Anti-GCNT1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Cow,Sheep) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Golgi apparatus membrane. |
| 组织特异性 | Highly expressed in activated T-lymphocytes and myeloid cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins. |
| 免疫原 | KLH conjugated synthetic peptide: Human GCNT1 |
| 抗原种属 | Human |
| 基因名称 | GCNT1 |
| 基因ID | |
| 蛋白名称 | beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase |
| Uniprot ID | |
| 功能 | Forms critical branches in O-glycans. |
| 分子量 | Theoretical: 50 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |