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Anti-PYCARD Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 2 可用于 WB。
Anti-PYCARD Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 2 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,975 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-PYCARD Polyclonal Antibody 2 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 2 can be used in WB. |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | Sample: Lane 1: Human U937 cell lysates Lane 2: Human THP-1 cell lysates Lane 3: Recombinant human ASC protein, His Primary: Anti-ASC/TMS1 (TMAB-01596) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kDa Observed band size: 22 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cytoplasm. Note=Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Tissue specificity: Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell lines HL-60 and U937, but not in Jurkat T-cell lymphoma and Daudi Burkitt's lymphoma. |
免疫原 | KLH conjugated synthetic peptide: human ASC |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Tumor biomarkers,Associated Proteins,CARD Family |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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