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Anti-PYCARD Polyclonal Antibody 2

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Anti-PYCARD Polyclonal Antibody 2
产品编号 TMAB-01596

Anti-PYCARD Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 2 可用于 WB。

Anti-PYCARD Polyclonal Antibody 2

Anti-PYCARD Polyclonal Antibody 2

Rating icon 还可以
Anti-PYCARD Polyclonal Antibody 2
产品编号 TMAB-01596

Anti-PYCARD Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PYCARD Polyclonal Antibody 2 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
交叉反应
Human
验证活性
Sample:
Lane 1: Human U937 cell lysates
Lane 2: Human THP-1 cell lysates
Lane 3: Recombinant human ASC protein, His
Primary: Anti-ASC/TMS1 (TMAB-01596) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kDa
Observed band size: 22 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Note=Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Tissue specificity: Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell lines HL-60 and U937, but not in Jurkat T-cell lymphoma and Daudi Burkitt's lymphoma.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ASC
抗原种属
Human
基因ID
Uniprot ID
研究领域
Tumor biomarkers,Associated Proteins,CARD Family
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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