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Anti-Retinoid X Receptor alpha Antibody (8D993)
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产品编号 TMAC-03587
别名 RXRalpha1, RXRA_HUMAN, Rxra, RXR alpha1, Retinoid X Receptorα, Retinoid X Receptoralpha, Retinoid X Receptora, Retinoid X Receptor α, Retinoid X receptor alpha, Retinoid X Receptor a, Retinoid X nuclear receptor alpha, Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR alpha, OTTHUMP00000022510, Nuclear receptor subfamily 2 group B member 1, NR2B1, MGC102720, FLJ16733, FLJ16020, FLJ00318, FLJ00280
Anti-Retinoid X Receptor alpha Antibody (8D993) 是一种 Rabbit 抗体，靶向 Retinoid X Receptor alpha。Anti-Retinoid X Receptor alpha Antibody (8D993) 可用于 WB,ICC,IF,IHC,IP。
Anti-Retinoid X Receptor alpha Antibody (8D993)
Anti-Retinoid X Receptor alpha Antibody (8D993)
还可以产品编号 TMAC-03587 别名 RXRalpha1, RXRA_HUMAN, Rxra, RXR alpha1, Retinoid X Receptorα, Retinoid X Receptoralpha, Retinoid X Receptora, Retinoid X Receptor α, Retinoid X receptor alpha, Retinoid X Receptor a, Retinoid X nuclear receptor alpha, Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR alpha, OTTHUMP00000022510, Nuclear receptor subfamily 2 group B member 1, NR2B1, MGC102720, FLJ16733, FLJ16020, FLJ00318, FLJ00280
Anti-Retinoid X Receptor alpha Antibody (8D993) 是一种 Rabbit 抗体，靶向 Retinoid X Receptor alpha。Anti-Retinoid X Receptor alpha Antibody (8D993) 可用于 WB,ICC,IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Retinoid X Receptor alpha Antibody (8D993) is a Rabbit antibody targeting Retinoid X Receptor alpha. Anti-Retinoid X Receptor alpha Antibody (8D993) can be used in WB,ICC,IF,IHC,IP. |
| 别名 | RXRalpha1, RXRA_HUMAN, Rxra, RXR alpha1, Retinoid X Receptorα, Retinoid X Receptoralpha, Retinoid X Receptora, Retinoid X Receptor α, Retinoid X receptor alpha, Retinoid X Receptor a, Retinoid X nuclear receptor alpha, Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR alpha, OTTHUMP00000022510, Nuclear receptor subfamily 2 group B member 1, NR2B1, MGC102720, FLJ16733, FLJ16020, FLJ00318, FLJ00280 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Retinoid X Receptor alpha on MCF-7 cell using anti-Retinoid X Receptor alpha antibody at 1/5,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-Retinoid X Receptor alpha antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-Retinoid X Receptor alpha antibody. Counter stained with hematoxylin. 4. ICC staining Retinoid X Receptor alpha in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Retinoid X Receptor alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200; IP: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: N-terminal human Retinoid X Receptor alpha |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 51 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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