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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-OLIG3 Polyclonal Antibody

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货号 TMAB-09768

Anti-OLIG3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OLIG3。Anti-OLIG3 Polyclonal Antibody 可用于 WB。

Anti-OLIG3 Polyclonal Antibody

Anti-OLIG3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09768

Anti-OLIG3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OLIG3。Anti-OLIG3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-OLIG3 Polyclonal Antibody is a Rabbit antibody targeting OLIG3. Anti-OLIG3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human OLIG3
抗原种属
Human
基因名称
OLIG3
基因ID
167826
蛋白名称
Oligodendrocyte transcription factor 3
Uniprot ID
Q7RTU3
功能
May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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