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Anti-Phospho-eNOS (Ser117) Polyclonal Antibody

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货号 TMAB-10645

Anti-Phospho-eNOS (Ser117) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-eNOS (Ser117)。Anti-Phospho-eNOS (Ser117) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-eNOS (Ser117) Polyclonal Antibody

Anti-Phospho-eNOS (Ser117) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10645

Anti-Phospho-eNOS (Ser117) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-eNOS (Ser117)。Anti-Phospho-eNOS (Ser117) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Phospho-eNOS (Ser117) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eNOS (Ser117). Anti-Phospho-eNOS (Ser117) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Sheep (predicted:Pig,Cow,Mouse,Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
组织特异性Platelets, placenta, liver and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: mouse eNOS around the phosphorylation site of Ser117
抗原种属
Mouse
基因名称
NOS3
基因ID
蛋白名称
Nitric oxide synthase, endothelial
Uniprot ID
功能
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
化学信息
分子量Theoretical: 133 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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