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Anti-Alkaline Phosphatase/ALPL Antibody (2T822) 是一种 Rabbit 抗体,靶向 Alkaline Phosphatase/ALPL。Anti-Alkaline Phosphatase/ALPL Antibody (2T822) 可用于 ELISA。
Anti-Alkaline Phosphatase/ALPL Antibody (2T822) 是一种 Rabbit 抗体,靶向 Alkaline Phosphatase/ALPL。Anti-Alkaline Phosphatase/ALPL Antibody (2T822) 可用于 ELISA。
产品描述 | Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2T822 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ALPI (rh ALPI; TMPY-02650; P09923; Met1-Asp503). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. ALPI mutations impaired either stability or catalytic activity of ALPI and rendered it unable to detoxify lipopolysaccharide-dependent signalling. ALPI mutations should be included in screening for monogenic causes of inflammatory bowel diseases and lay the groundwork for ALPI-based treatments in intestinal inflammatory disorders. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ALPI protein (TMPY-02650) |
抗原种属 | Human |
研究领域 | Phosphatases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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