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Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PLCB3 (Ser1105)。Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody 可用于 ICC/IF,FCM。
Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PLCB3 (Ser1105)。Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody 可用于 ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCB3 (Ser1105). Anti-Phospho-PLCB3 (Ser1105) Polyclonal Antibody can be used in ICC/IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse) |
| 应用 | ICC/IFFCM |
| 推荐剂量 | ICC/IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Peripheral membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human PLC beta3 around the phosphorylation site of Ser1105 |
| 抗原种属 | Human |
| 基因名称 | PLCB3 |
| 基因ID | |
| 蛋白名称 | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-3 |
| Uniprot ID | |
| 功能 | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. |
| 分子量 | Theoretical: 136 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |