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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD253 Monoclonal Antibody (9G813)

Synonyms: TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L
货号 TMAT-0343 一键复制产品信息
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Anti-CD253 Monoclonal Antibody (9G813) 是一种 Mouse 抗体，靶向 CD253。Anti-CD253 Monoclonal Antibody (9G813) 可用于 FCM。

Anti-CD253 Monoclonal Antibody (9G813)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0343

别名 TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L

Anti-CD253 Monoclonal Antibody (9G813) 是一种 Mouse 抗体，靶向 CD253。Anti-CD253 Monoclonal Antibody (9G813) 可用于 FCM。

Anti-CD253 Monoclonal Antibody (9G813)
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产品介绍

生物活性
产品描述
Anti-CD253 Monoclonal Antibody (9G813) is a Mouse antibody targeting CD253. Anti-CD253 Monoclonal Antibody (9G813) can be used in FCM.
别名
TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L
Ig Type
IgG1
克隆号
9G813
反应种属
Human
应用FCM
推荐剂量
FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD253 (AA: extra 39-281) expressed in E. Coli.
抗原种属
Human
基因名称
TNFSF10
基因ID
8743
蛋白名称
Tumor necrosis factor ligand superfamily member 10
Uniprot ID
P50591
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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