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Anti-CD33 Monoclonal Antibody (8V589) 是一种 Mouse 抗体,靶向 CD33。Anti-CD33 Monoclonal Antibody (8V589) 可用于 WB,IHC,FCM。
别名 SIGLEC-3, SIGLEC3, p67
Anti-CD33 Monoclonal Antibody (8V589) 是一种 Mouse 抗体,靶向 CD33。Anti-CD33 Monoclonal Antibody (8V589) 可用于 WB,IHC,FCM。

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| 产品描述 | Anti-CD33 Monoclonal Antibody (8V589) is a Mouse antibody targeting CD33. Anti-CD33 Monoclonal Antibody (8V589) can be used in WB,IHC,FCM. |
| 别名 | SIGLEC-3, SIGLEC3, p67 |
| Ig Type | IgG1 |
| 克隆号 | 8V589 |
| 反应种属 | Human |
| 应用 | WBIHCFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD) |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CD33 |
| 基因ID | |
| 蛋白名称 | Myeloid cell surface antigen CD33 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |