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顶部生物活性储存和溶解信息计算器

Anti-CD160 Antibody (5N54)

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产品编号 TMAY-02272

别名 CD160 molecule, By55, AU045688

Anti-CD160 Antibody (5N54) 是一种 Mouse 抗体，靶向 CD160。Anti-CD160 Antibody (5N54) 可用于 FCM。

Anti-CD160 Antibody (5N54)

Anti-CD160 Antibody (5N54)

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产品编号 TMAY-02272 别名 CD160 molecule, By55, AU045688

Anti-CD160 Antibody (5N54) 是一种 Mouse 抗体，靶向 CD160。Anti-CD160 Antibody (5N54) 可用于 FCM。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD160 Antibody (5N54) is a Mouse antibody targeting CD160. Anti-CD160 Antibody (5N54) can be used in FCM.
别名CD160 molecule, By55, AU045688
Ig Type
Mouse IgG2b
克隆号
5N54
交叉反应
Human
特异性
Human CD160
验证活性
Flow cytometric analysis of Human CD160 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD160, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD160 / NK1 / BY55 (rh CD160 / NK1 / BY55; TMPY-01905; NP_008984.1; Met1-Leu158). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human CD160 / NK1 / BY55 Protein (TMPY-01905)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AU-045688AU 045688

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4个月前
5.0
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