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Anti-IL-12B Antibody (8D284)

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产品编号 TMAY-00188

别名 interleukin 12B

Anti-IL-12B Antibody (8D284) 是一种 Mouse 抗体，靶向 IL-12B。Anti-IL-12B Antibody (8D284) 可用于 ELISA(Cap)。

Anti-IL-12B Antibody (8D284)

Anti-IL-12B Antibody (8D284)

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产品编号 TMAY-00188 别名 interleukin 12B

Anti-IL-12B Antibody (8D284) 是一种 Mouse 抗体，靶向 IL-12B。Anti-IL-12B Antibody (8D284) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 795
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100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-12B Antibody (8D284) is a Mouse antibody targeting IL-12B. Anti-IL-12B Antibody (8D284) can be used in ELISA(Cap).
别名interleukin 12B
Ig Type
Mouse IgG1
克隆号
8D284
交叉反应
Human
特异性
Human IL-12 p40/IL12B
应用ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL12B / IL-12B (rh IL12B / IL-12B; TMPY-01045; NP_002178.2; Met1-Ser328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0
研究背景Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. IL12B/IL-12B associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine that functions in innate and adaptive immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human IL12B / IL-12B Protein (TMPY-01045)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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