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Anti-NEFH Antibody (9C4)

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Anti-NEFH Antibody (9C4)
产品编号 TMAC-02807
别名 NF-H, NFH, Neurofilament triplet H protein, Neurofilament heavy polypeptide, NEFH, KIAA0845, 200 kDa neurofilament protein

Anti-NEFH Antibody (9C4) 是一种 Mouse 抗体,靶向 NEFH。Anti-NEFH Antibody (9C4) 可用于 WB,IP,IF,IHC-P。

Anti-NEFH Antibody (9C4)

Anti-NEFH Antibody (9C4)

Rating icon 还可以
Anti-NEFH Antibody (9C4)
产品编号 TMAC-02807 别名 NF-H, NFH, Neurofilament triplet H protein, Neurofilament heavy polypeptide, NEFH, KIAA0845, 200 kDa neurofilament protein

Anti-NEFH Antibody (9C4) 是一种 Mouse 抗体,靶向 NEFH。Anti-NEFH Antibody (9C4) 可用于 WB,IP,IF,IHC-P。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,980
5日内发货
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产品介绍

生物活性
产品描述
Anti-NEFH Antibody (9C4) is a Mouse antibody targeting NEFH. Anti-NEFH Antibody (9C4) can be used in WB,IP,IF,IHC-P.
别名NF-H, NFH, Neurofilament triplet H protein, Neurofilament heavy polypeptide, NEFH, KIAA0845, 200 kDa neurofilament protein
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of NF-H expression in rat brain (A) and mouse brain (B) tissue extracts.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing membrane and cytoplasmic staining of Purkinje cells and neuropil staining in granular layer and molecular layer (A). Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing membrane and cytoplasmic staining of Purkinje cells and neuropil staining in granular layer and molecular layer (B).
应用
推荐剂量
WB: 1:500-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Neurofilament-H (NF-H), for neurofilament heavy polypeptide, a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and Actin filaments. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease and Alzheimer's disease.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A neurofilament NF-H protein isolated from a cytoskeletal preparation from brain tissue homogenate of calf origin
Uniprot ID
化学信息
分子量Theoretical: 200 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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