Anti-PD-1 Antibody (2F89)

Name: Anti-PD-1 Antibody (2F89)
Brand: TargetMol
SKU: TMAY-03666
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03666

别名 SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (2F89) 是一种 Rabbit 抗体，靶向 PD-1。Anti-PD-1 Antibody (2F89) 可用于 ELISA。

Anti-PD-1 Antibody (2F89)

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Anti-PD-1 Antibody (2F89)

还可以

产品编号 TMAY-03666 别名 SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (2F89) 是一种 Rabbit 抗体，靶向 PD-1。Anti-PD-1 Antibody (2F89) 可用于 ELISA。

规格	价格	库存	数量
20 μL	¥ 795	5日内发货
100 μL	¥ 2,279	5日内发货

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生物活性

产品描述	Anti-PD-1 Antibody (2F89) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (2F89) can be used in ELISA.
别名	SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Ig Type	Rabbit IgG
克隆号	2F89
交叉反应	Canine
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Canine PD1 / PDCD1 / CD279 ( TMPY-04342; XP_022265285.1; Met1-Leu169).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. Furthermore, PD1 is shown to be a regulator of virus-specific CD8+ T cell survival in HIV infection. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Blockade: Blocking AntibodiImmune Checkpoint Blockade: PD1 / PDCD1 / CD2Immune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyPD1 / PDCD1 / CD279 Immune CheckpointPD1 / PDCD1 / CD279 Immune Checkpoint AntibodPD1 / PDCD1 / CD279 Immune Checkpoint ProteinTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Protein: Canine PD1 / PDCD1 / CD279 Protein (TMPY-04342)
抗原种属	Canine
研究领域	ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.