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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DAPK2 Polyclonal Antibody

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货号 TMAB-04978

Anti-DAPK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DAPK2。Anti-DAPK2 Polyclonal Antibody 可用于 WB。

Anti-DAPK2 Polyclonal Antibody

Anti-DAPK2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04978

Anti-DAPK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DAPK2。Anti-DAPK2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-DAPK2 Polyclonal Antibody is a Rabbit antibody targeting DAPK2. Anti-DAPK2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cytoplasmic vesicle, autophagosome lumen.
组织特异性Ubiquitously expressed with highest levels found in skeletal muscles, heart, kidney and brain. Isoform 1 is brain-specific. Isoform 2 and isoform 3 are predominantly expressed in testis and skeletal muscles respectively. Isoform 4 is weakly expressed in brain, heart and kidney. Isoform 5 is dominantly expressed in liver, heart and kidney. Isoform 6 is expressed in neurons.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Protein kinase termed (DAPK2) dependant on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DAPK2
抗原种属
Human
基因名称
DAPK2
基因ID
23604
蛋白名称
Death-associated protein kinase 2
Uniprot ID
Q9UIK4
功能
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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