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顶部生物活性储存和溶解信息计算器

Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738)

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Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738)
产品编号 TMAY-01658
别名 STAT6C, STAT6B, Stat6 (p-Y641), Stat6 (p-Tyr641), STAT-6, p-Stat6 (Y641), p-Stat6 (Tyr641), Phospho-Stat6 (Y641), IL-4-STAT, HIES6, D12S1644

Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) 是一种 Rabbit 抗体，靶向 Phospho-STAT6 (Tyr641)。Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) 可用于 WB。

Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738)
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Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738)

Rating icon 还可以
Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738)
产品编号 TMAY-01658 别名 STAT6C, STAT6B, Stat6 (p-Y641), Stat6 (p-Tyr641), STAT-6, p-Stat6 (Y641), p-Stat6 (Tyr641), Phospho-Stat6 (Y641), IL-4-STAT, HIES6, D12S1644

Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) 是一种 Rabbit 抗体，靶向 Phospho-STAT6 (Tyr641)。Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) 可用于 WB。

规格价格库存数量
20 μL
¥ 684
5日内发货
100 μL
¥ 1,979
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) is a Rabbit antibody targeting Phospho-STAT6 (Tyr641). Anti-Phospho-STAT6 (Tyr641) Antibody (6Y738) can be used in WB.
别名STAT6C, STAT6B, Stat6 (p-Y641), Stat6 (p-Tyr641), STAT-6, p-Stat6 (Y641), p-Stat6 (Tyr641), Phospho-Stat6 (Y641), IL-4-STAT, HIES6, D12S1644
Ig Type
Rabbit IgG
克隆号
6Y738
交叉反应
Human;
Species predicted to react based on 100% sequence homology: Cynomolgus, Bovin, Pig, Chicken
验证活性
1. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with IL4 (100 ng/mL, 15min; +), using Phospho-Stat6 (Tyr641) Antibody, Rabbit MAb at 1:10000 dilution (upper) or Anti-STAT6 Antibody, Rabbit PAb at 1:1000 dilution (lower).
2. Western blot analysis of extracts from serum-starved Hela, treated with IL4 (100 ng/mL, 15 min), using Phospho-Stat6 (Tyr641) Antibody, Rabbit MAb and other brands’ antibodies (Company C) at dilution of 1:1000, 1:10000 and 1:200000.
3. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with IL4 using Phospho-Stat6 (Tyr641) Antibody, Rabbit MAb at 1:10000 dilution. (Validation Experiment)
4. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with IL4 or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-Stat6 (Tyr641) Antibody, Rabbit MAb at 1:10000 dilution. (Validation Experiment)
应用
WB
推荐剂量
WB: 1:2000-1:20000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr641 of the Human Stat6.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: residues around Tyr641 of the Human Stat6
抗原种属
Human
研究领域
Apoptosis Transcription Factors and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

Stat6 (pY641)Stat6 (pTyr641)Stat6 (phospho-Y641)Stat6 (phospho-Tyr641)pStat6 (Y641)pStat6 (Tyr641)

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