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Anti-SNCA Antibody (9C948)
还可以产品编号 TMAH-01115
别名 PD1, PARK4, PARK1, NACP
Anti-SNCA Antibody (9C948) 是一种抗体，靶向 SNCA。Anti-SNCA Antibody (9C948) 可用于 ELISA, IHC。
Anti-SNCA Antibody (9C948)
Anti-SNCA Antibody (9C948)
还可以产品编号 TMAH-01115 别名 PD1, PARK4, PARK1, NACP
Anti-SNCA Antibody (9C948) 是一种抗体，靶向 SNCA。Anti-SNCA Antibody (9C948) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SNCA Antibody (9C948) is an antibody targeting SNCA. Anti-SNCA Antibody (9C948) can be used in ELISA, IHC. |
| 别名 | PD1, PARK4, PARK1, NACP |
| Ig Type | Rabbit IgG |
| 克隆号 | 9C948 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-01115 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Alpha Synuclein |
| 抗原种属 | Human |
| 基因ID | 6622 |
| Uniprot ID | |
| 研究领域 | Neuroscience |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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