Name: EZH2-IN-5
Brand: TargetMol
SKU: T38827
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 10,600

6-8周

生物活性

产品描述	EZH2-IN-5 is a highly effective inhibitor of EZH2, displaying remarkable potency against both wild-type and mutant Tyr641 EZH2, with IC50 values of 1.52 nM and 4.07 nM, respectively.
靶点活性	EZH2 (Y641F):4.07 nM (IC50), EZH2 (WT):1.52 nM (IC50)
体外活性	EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC 50 of 187.28 nM[1].
别名	EZH2-IN-5

化学信息

分子量	517.512
分子式	C₂₆H₃₇BrN₄O₂
CAS No.	1403258-69-4
Smiles	CCN([C@H]1CC[C@@H](CC1)N(C)C)c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C \|wU:3.2,wD:6.9,(,1.54,;;-1.33,-.77,;-2.67,,;-4,-.77,;-5.33,,;-5.33,1.54,;-4,2.31,;-2.67,1.54,;-6.67,2.31,;-8,1.54,;-6.67,3.85,;-1.33,-2.31,;-2.67,-3.08,;-2.67,-4.62,;-4,-5.39,;-1.33,-5.39,;,-4.62,;1.33,-5.39,;2.67,-4.62,;1.33,-6.93,;2.67,-7.7,;2.67,-9.24,;4,-10.01,;5.33,-9.24,;4,-11.55,;2.67,-12.32,;2.67,-13.86,;1.33,-11.55,;1.33,-10.01,;,-9.24,;,-3.08,;1.33,-2.31,)\|