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别名 CAY10719
CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.

CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 2,130 | 35日内发货 | |
| 5 mg | ¥ 3,660 | 35日内发货 | |
| 10 mg | ¥ 6,330 | 35日内发货 | |
| 25 mg | ¥ 12,800 | 35日内发货 |
| 产品描述 | CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity. |
| 别名 | CAY10719 |
| 分子量 | 451.34 |
| 分子式 | C25H20Cl2N2O2 |
| CAS No. | 1942919-63-2 |
| Smiles | C(=O)(N1C(C2=C(C=3C(N2)=CC=CC3)CC1)C4=CC(Cl)=C(Cl)C=C4)C5=CC=C(OC)C=C5 |
| 密度 | 1.372 g/cm3 (Predicted) |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度信息 | DMF: 20 mg/mL (44.31 mM), Sonication is recommended. DMF:PBS(pH7.2) (1:2): 0.33 mg/mL (0.73 mM), Sonication is recommended. DMSO: 2 mg/mL (4.43 mM), Sonication is recommended. |
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