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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PDX1 Polyclonal Antibody

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货号 TMAB-10152

Anti-PDX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDX1。Anti-PDX1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PDX1 Polyclonal Antibody

Anti-PDX1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10152

Anti-PDX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDX1。Anti-PDX1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDX1 Polyclonal Antibody is a Rabbit antibody targeting PDX1. Anti-PDX1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Pig)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PDX1
抗原种属
Human
基因名称
PDX1
基因ID
3651
蛋白名称
Pancreas/duodenum homeobox protein 1
Uniprot ID
P52945
功能
Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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