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顶部生物活性储存和溶解信息计算器

Anti-NT5E Antibody (1N164)

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Anti-NT5E Antibody (1N164)
产品编号 TMAC-00733
别名 NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)

Anti-NT5E Antibody (1N164) 是一种 Rabbit 抗体，靶向 NT5E。Anti-NT5E Antibody (1N164) 可用于 WB,IHC。

Anti-NT5E Antibody (1N164)

Anti-NT5E Antibody (1N164)

Rating icon 还可以
Anti-NT5E Antibody (1N164)
产品编号 TMAC-00733 别名 NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)

Anti-NT5E Antibody (1N164) 是一种 Rabbit 抗体，靶向 NT5E。Anti-NT5E Antibody (1N164) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-NT5E Antibody (1N164) is a Rabbit antibody targeting NT5E. Anti-NT5E Antibody (1N164) can be used in WB,IHC.
别名NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of CD73 on A431 cells lysates using anti-CD73 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD73 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-CD73 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-CD73 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景CD73 (also designated ecto-5'-nucleotidase, E5NT, NT, NT5, NTE, eN and eNT) is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts. For example, IgG mediated neutralization of CD73 interferes with lymphocyte adhesion to EC, and blocks aggregation of germinal center B cells and follicular dendritic cells. Furthermore, IgG-mediated targeting of lymphocyte CD73, but not of endothelial cell CD73, causes shedding of CD73 and tyrosine phosphorylation of proteins.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P21589
化学信息
分子量Theoretical: 70 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

NT-5NT 5CD-73CD 735'-nucleotidase, ecto

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