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Anti-LDLR Antibody-FITC (3N325)
还可以产品编号 TMAY-03221F
Anti-LDLR Antibody-FITC (3N325) 是一种 FITC-conjugated Rabbit 抗体，靶向 LDLR。Anti-LDLR Antibody-FITC (3N325) 可用于 FCM。
Anti-LDLR Antibody-FITC (3N325)
Anti-LDLR Antibody-FITC (3N325)
还可以产品编号 TMAY-03221F
Anti-LDLR Antibody-FITC (3N325) 是一种 FITC-conjugated Rabbit 抗体，靶向 LDLR。Anti-LDLR Antibody-FITC (3N325) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-LDLR Antibody-FITC (3N325) is a FITC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-FITC (3N325) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3N325 |
| 交叉反应 | Mouse |
| 验证活性 | Profile of anti-LDLR reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with FITC Rabbit anti-LDLR. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LDLR / LDL Receptor (rM LDLR / LDL Receptor; TMPY-01014; NP_034830.2; Met 1-Arg 790) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/PerCP/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Mouse LDLR / LDL Receptor protein (TMPY-01014) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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