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Anti-LDLR Antibody-FITC (3N325)

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Anti-LDLR Antibody-FITC (3N325)
产品编号 TMAY-03221F
别名 low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH

Anti-LDLR Antibody-FITC (3N325) 是一种 FITC-conjugated Rabbit 抗体,靶向 LDLR。Anti-LDLR Antibody-FITC (3N325) 可用于 FCM。

Anti-LDLR Antibody-FITC (3N325)
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Anti-LDLR Antibody-FITC (3N325)

Rating icon 还可以
Anti-LDLR Antibody-FITC (3N325)
产品编号 TMAY-03221F 别名 low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH

Anti-LDLR Antibody-FITC (3N325) 是一种 FITC-conjugated Rabbit 抗体,靶向 LDLR。Anti-LDLR Antibody-FITC (3N325) 可用于 FCM。

规格价格库存数量
25 T
¥ 885
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100 T
¥ 1,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-LDLR Antibody-FITC (3N325) is a FITC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-FITC (3N325) can be used in FCM.
别名low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH
Ig Type
Rabbit IgG
克隆号
3N325
交叉反应
Mouse
验证活性
Profile of anti-LDLR reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with FITC Rabbit anti-LDLR.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LDLR / LDL Receptor (rM LDLR / LDL Receptor; TMPY-01014; NP_034830.2; Met 1-Arg 790) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/PerCP/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Mouse LDLR / LDL Receptor protein (TMPY-01014)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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