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Anti-FbxL12 Polyclonal Antibody

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货号 TMAB-05918

Anti-FbxL12 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FbxL12。Anti-FbxL12 Polyclonal Antibody 可用于 WB。

Anti-FbxL12 Polyclonal Antibody

Anti-FbxL12 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05918

Anti-FbxL12 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FbxL12。Anti-FbxL12 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-FbxL12 Polyclonal Antibody is a Rabbit antibody targeting FbxL12. Anti-FbxL12 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for proteasomal degradation. FBL12 (F-box and leucine-rich repeat protein 12), also designated FBXL12, is a 326 amino acid protein that contains one F-box domain, five LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. FBL12 interacts with both Skp1 and CUL-1, and is encoded by a gene that maps to human chromosome 19p13.2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FbxL12
抗原种属
Human
基因名称
FBXL12
基因ID
蛋白名称
F-box/LRR-repeat protein 12
Uniprot ID
功能
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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