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Niraparib metabolite M1 HCl(尼拉帕尼代谢物 M1 盐酸盐)是Niraparib的活性代谢产物,作为新型的靶向 ADP核糖聚合酶(Poly ADP-ribose Polymerase, PARP)抑制剂,能够竞争性抑制 PARP1 和 PARP2阻止肿瘤细胞的DNA修复机制从而有效抑制生长和扩散,常用于研究卵巢癌、输卵管癌和原发性腹膜癌。
Niraparib metabolite M1 HCl(尼拉帕尼代谢物 M1 盐酸盐)是Niraparib的活性代谢产物,作为新型的靶向 ADP核糖聚合酶(Poly ADP-ribose Polymerase, PARP)抑制剂,能够竞争性抑制 PARP1 和 PARP2阻止肿瘤细胞的DNA修复机制从而有效抑制生长和扩散,常用于研究卵巢癌、输卵管癌和原发性腹膜癌。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,245 | In stock | |
5 mg | ¥ 3,650 | In stock | |
10 mg | ¥ 5,475 | In stock | |
25 mg | ¥ 9,310 | In stock | |
50 mg | ¥ 13,965 | In stock | |
100 mg | ¥ 19,980 | In stock | |
1 mL x 10 mM (in DMSO) | ¥ 2,582 | In stock |
Niraparib metabolite M1 HCl 相关产品
产品描述 | Niraparib metabolite M1 HCl is the active metabolite of Niraparib, as a novel targeted ADP ribose polymerase (PARP) inhibitor, it can competitively inhibit PARP1 and PARP2 to block the DNA repair mechanism of tumor cells and thus effectively inhibit the growth and proliferation, which is commonly used in the study of ovarian cancer, fallopian tube cancer and primary peritoneal cancer, and is commonly used in the study of ovarian, fallopian tube and primary peritoneal cancers. |
别名 | 尼拉帕尼代谢物 M1 盐酸盐, Niraparib metabolite M1 HCl (1476777-06-6 Free base), Niraparib carboxylic acid metabolite M1 HCl, M1 metabolite of niraparib HCl |
分子量 | 357.83 |
分子式 | C19H20ClN3O2 |
Smiles | OC(C1=CC=CC2=CN(C3=CC=C([C@@H]4CCCNC4)C=C3)N=C12)=O.Cl |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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