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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-FMR1 Antibody (9X925)

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货号 TMAC-01524

别名 zgc:66226, wu:fd18c10, wu:fb16f11, Protein FMR-1, Protein FMR1, POF1, POF, MGC87458, fxr1, FRAXA, fragile X mental retardation, autosomal homolog 1, fragile X mental retardation syndrome-related protein 1, Fragile X mental retardation protein 1, Fragile X mental retardation protein, Fragile X mental retardation 1 protein, Fragile X mental retardation 1, FMRP, FMR1_HUMAN, Fmr1 gene, Fmr1, FMR 1

Anti-FMR1 Antibody (9X925) 是一种 Rabbit 抗体，靶向 FMR1。Anti-FMR1 Antibody (9X925) 可用于 ICC/IF,IHC,WB。

Anti-FMR1 Antibody (9X925)

Anti-FMR1 Antibody (9X925)

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Rating icon 还可以
货号 TMAC-01524 别名 zgc:66226, wu:fd18c10, wu:fb16f11, Protein FMR-1, Protein FMR1, POF1, POF, MGC87458, fxr1, FRAXA, fragile X mental retardation, autosomal homolog 1, fragile X mental retardation syndrome-related protein 1, Fragile X mental retardation protein 1, Fragile X mental retardation protein, Fragile X mental retardation 1 protein, Fragile X mental retardation 1, FMRP, FMR1_HUMAN, Fmr1 gene, Fmr1, FMR 1

Anti-FMR1 Antibody (9X925) 是一种 Rabbit 抗体，靶向 FMR1。Anti-FMR1 Antibody (9X925) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-FMR1 Antibody (9X925) is a Rabbit antibody targeting FMR1. Anti-FMR1 Antibody (9X925) can be used in ICC/IF,IHC,WB.
别名zgc:66226, wu:fd18c10, wu:fb16f11, Protein FMR-1, Protein FMR1, POF1, POF, MGC87458, fxr1, FRAXA, fragile X mental retardation, autosomal homolog 1, fragile X mental retardation syndrome-related protein 1, Fragile X mental retardation protein 1, Fragile X mental retardation protein, Fragile X mental retardation 1 protein, Fragile X mental retardation 1, FMRP, FMR1_HUMAN, Fmr1 gene, Fmr1, FMR 1
Ig Type
IgG
克隆号
9X925
反应种属
Human,Mouse,Rat
验证活性
1. Western blot analysis of FMRP on different cells lysates using anti-FMRP antibody at 1/500 dilution. Positive control: Lane 1: Hela, Lane 2: K562.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FMRP antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-FMRP antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-FMRP antibody. Counter stained with hematoxylin.
5. ICC staining FMRP in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining FMRP in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining FMRP in SH-SY5Y cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICC/IFIHCWB
推荐剂量
WB: 1:5000-10000; IHC: 1:50-200; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene. In fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 localizes to both the nucleus and the cytoplasm and can also interact with two fragile X syndrome related factors, FXR1 and FXR2, which form heterodimers through their N-terminal coiled-coil domains. Since FMR1 contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleocytoplasmic transport of mRNAs.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q06787
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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