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Anti-CEACAM1 Antibody (7F98)
还可以产品编号 TMAY-01215
Anti-CEACAM1 Antibody (7F98) 是一种 Mouse 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody (7F98) 可用于 ELISA,ELISA(Det),IHC-P,FCM。
Anti-CEACAM1 Antibody (7F98)
Anti-CEACAM1 Antibody (7F98)
还可以产品编号 TMAY-01215
Anti-CEACAM1 Antibody (7F98) 是一种 Mouse 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody (7F98) 可用于 ELISA,ELISA(Det),IHC-P,FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CEACAM1 Antibody (7F98) is a Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody (7F98) can be used in ELISA,ELISA(Det),IHC-P,FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7F98 |
| 交叉反应 | Human; Not React with:Mouse, Rat |
| 验证活性 | 1. Immunochemical Staining of human CEACAM1 in human liver with Mouse Monoclonal Antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to bile canaliculus. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein). 2. Immunochemical Staining of human CEACAM1 in human colon carcinoma with Mouse Monoclonal Antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of epithelial cells. 3. Flow cytometric analysis of Human CEACAM1(CD66a) expression in HT-29 cells. |
| 应用 | ELISA,ELISA(Det),IHC-P,FCM |
| 推荐剂量 | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200; FCM: 1:25-1:100; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM1 / CD66a (rh CEACAM1; TMPY-00717; NP_001020083.1; Met 1-Gly 428). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| 研究背景 | The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD66a protein (TMPY-00717) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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