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CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) V2

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产品编号 TMPY-05669U

CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) V2 is expressed in HEK293 Cells. The accession number is P01732-1(CD8 alpha)&P10966-1(CD8 beta).

CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) V2

一键复制产品信息

产品编号 TMPY-05669U

CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) V2 is expressed in HEK293 Cells. The accession number is P01732-1(CD8 alpha)&P10966-1(CD8 beta).

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产品信息

生物活性	Immobilized Human CD8A&CD8B, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 15.2 ng/ml determined by ELISA.
产品描述	CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) V2 is expressed in HEK293 Cells. The accession number is P01732-1(CD8 alpha)&P10966-1(CD8 beta).
种属	Human
表达系统	HEK293 Cells
蛋白编号	P01732-1(CD8 alpha)&P10966-1(CD8 beta)
蛋白构建	Ser22-Asp182(CD8 alpha) acidic tail & Leu22-Pro170(CD8 beta) basic tail
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	23.54 kDa (CD8 alpha) and 22.62 kDa (CD8 beta) (Predicted); 26-28 kDa (CD8 alpha) and 28-32 kDa (CD8 beta) (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	CD8 alphaβ (CD8αβ) is a heterodimeric form of CD8. CD8α is required for surface expression of CD8β. The extracellular IgV-like domain of CD8α interacts with the α3 portion of the class I MHC molecule. CD8αβ is expressed on human peripheral T cells and functions as a coreceptor and can greatly increase the sensitivity and breadth of antigen recognition by CD8+peripheral T cells bearing TCR.