生物活性

产品描述	HLA-A11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein, Human, MHC (His) is expressed in HEK293 Cells. The accession number is AAV53343.1(HLA-A11:01)&P61769(B2M)&KITDFGLAK.
生物活性	Human HLA-A11:01&B2M&EGFR WT (KITDFGLAK) Monomer, His Tag captured on CM5 Chip via Anti-His Antibody can bind HLA-A11:01&B2M&EGFR TCR with an affinity constant of 0.34 µM as determined in SPR assay (Biacore T200).
研究背景	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	AAV533431 (HLA-A*11:01) & P61769 (B2M) & KITDFGLAK
蛋白构建	Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and KITDFGLAK peptide
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Supplied as 0.22 μm filtered solution in PBS, 200 mM L-arginine (pH 7.4).
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	48.50 kDa (Predicted); 50-60 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

**HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein, Human, MHC (His)**

HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein, Human, MHC (His)

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