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Anti-MYH11 Antibody (1K373)

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Anti-MYH11 Antibody (1K373)
产品编号 TMAY-00191
别名 VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4

Anti-MYH11 Antibody (1K373) 是一种 Rabbit 抗体，靶向 MYH11。Anti-MYH11 Antibody (1K373) 可用于 IHC-P。

Anti-MYH11 Antibody (1K373)
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Anti-MYH11 Antibody (1K373)

Rating icon 还可以
Anti-MYH11 Antibody (1K373)
产品编号 TMAY-00191 别名 VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4

Anti-MYH11 Antibody (1K373) 是一种 Rabbit 抗体，靶向 MYH11。Anti-MYH11 Antibody (1K373) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P.
别名VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4
Ig Type
Rabbit IgG
克隆号
1K373
交叉反应
Human
验证活性
1. Immunochemical staining of human MYH11 in human prostate with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human MYH11 in human smooth muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human MYH11. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. MYH11 functions as a contractile protein, converting chemical energy into mechanical energy through adenosine triphosphate hydrolysis.MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. Mutations in myosin heavy chain (MYH11) cause autosomal dominant inheritance of thoracic aortic aneurysms and dissections. At the same time, rare, nonsynonymous variants in MYH11 that are predicted to disrupt protein function but do not cause inherited aortic disease are common in the general population. The human smooth muscle myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: center region of the Human MYH11
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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