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Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753)
还可以产品编号 TMAY-01540
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) 是一种 Rabbit 抗体，靶向 Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F。Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) 可用于 WB,ELISA(Det)。
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753)
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753)
还可以产品编号 TMAY-01540
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) 是一种 Rabbit 抗体，靶向 Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F。Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) 可用于 WB,ELISA(Det)。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) is a Rabbit antibody targeting Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F. Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (8L753) can be used in WB,ELISA(Det). |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8L753 |
| 验证活性 | Anti-RSV-F rabbit monoclonal antibody at 1:1000 dilution. -Sample: Recombinant Protein 10 ng -Lane A: RSV Pre-F (A2) Protein -Lane B: RSV Post-F Protein -Lane C: RSV-F (A2) Protein -Lane D: RSV-F (Strain RSS-2) Protein -Lane E: RSV-F (aa 1-525) Protein -Lane F: RSV-F (aa 1-526) Protein -Lane G: RSV-F (A, strain Long) Protein -Lane H: RSV-F (B, strain 18537) Protein -Lane I: RSVB Post-F Protein -Lane J: RSV-preF Protein -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| 应用 | WB,ELISA(Det) |
| 推荐剂量 | WB: 1:1000-1:5000; ELISA(Det): 1:1000-1:10000; LFA(Det): 1-2 mg/mL |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F ( TMPY-01078; P03420.1; Met1-Thr529). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. The G protein mediates attachment of the virus to cell surface receptors, while the F protein promotes fusion of the viral and cellular membranes, allowing entry of the virus ribonucleoprotein into the cell cytoplasm. The fusion (F) protein of RSV is synthesized as a nonfusogenic precursor protein (F), which during its migration to the cell surface is activated by cleavage into the disulfide-linked F1 and F2 subunits. This fusion is pH independent and occurs directly at the outer cell membrane, and the F2 subunit was identifed as the major determinant of RSV host cell specificity. The trimer of F1-F2 interacts with glycoprotein G at the virion surface. Upon binding of G to heparan sulfate, the hydrophobic fusion peptide is unmasked and induces the fusion between host cell and virion membranes. Notably, RSV fusion protein is unique in that it is able to interact directly with heparan sulfate and therefore is sufficient for virus infection. Furthermore, the fusion protein is also able to trigger p53-dependent apoptosis. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/HRP |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F Protein (TMPY-01078) |
| 抗原种属 | RSV |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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