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Anti-PTK2 Antibody (4L758)
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产品编号 TMAC-01432
别名 PTK 2, Protein-tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, p125FAK, FRNK, Focal adhesion kinase-related nonkinase, Focal adhesion kinase 1, FAK1, FAK, FADK 1, EC 2.7.10.2
Anti-PTK2 Antibody (4L758) 是一种 Rabbit 抗体，靶向 PTK2。Anti-PTK2 Antibody (4L758) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-PTK2 Antibody (4L758)
Anti-PTK2 Antibody (4L758)
还可以产品编号 TMAC-01432 别名 PTK 2, Protein-tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, p125FAK, FRNK, Focal adhesion kinase-related nonkinase, Focal adhesion kinase 1, FAK1, FAK, FADK 1, EC 2.7.10.2
Anti-PTK2 Antibody (4L758) 是一种 Rabbit 抗体，靶向 PTK2。Anti-PTK2 Antibody (4L758) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-PTK2 Antibody (4L758) is a Rabbit antibody targeting PTK2. Anti-PTK2 Antibody (4L758) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | PTK 2, Protein-tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, p125FAK, FRNK, Focal adhesion kinase-related nonkinase, Focal adhesion kinase 1, FAK1, FAK, FADK 1, EC 2.7.10.2 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of FAK on different lysates using anti-FAK antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded huamn liver cancer tissue using anti-FAK antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-FAK antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-FAK antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-FAK antibody. Counter stained with hematoxylin. 6. ICC staining FAK in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining FAK in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of Hela cells with FAK antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Focal adhesion kinase was initially identified as a major substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only those basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the reepithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein coupled receptors. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 119 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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