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Anti-Cadherin 6/CDH6 Antibody (5U203)
还可以产品编号 TMAY-00362
Anti-Cadherin 6/CDH6 Antibody (5U203) 是一种 Mouse 抗体，靶向 Cadherin 6/CDH6。Anti-Cadherin 6/CDH6 Antibody (5U203) 可用于 ELISA。
Anti-Cadherin 6/CDH6 Antibody (5U203)
Anti-Cadherin 6/CDH6 Antibody (5U203)
还可以产品编号 TMAY-00362
Anti-Cadherin 6/CDH6 Antibody (5U203) 是一种 Mouse 抗体，靶向 Cadherin 6/CDH6。Anti-Cadherin 6/CDH6 Antibody (5U203) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Cadherin 6/CDH6 Antibody (5U203) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (5U203) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5U203 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cadherin-6 / K-Cadherin / CDH6 (rh Cadherin-6 / K-Cadherin / CDH6; TMPY-01050; NP_004923.1; Met 1-Ala 615). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progression in a number of adenocarcinomas. Cadherin-6 (CDH6), also known as K-cadherin (KCAD), is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains an 18 aa signal peptide, a 35 aa propeptide, a 562 aa extracellular region, a 21 aa transmembrane segment, and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular region. Cadherin-6 is highly expressed in brain, cerebellum, and kidney, and may contribute to the formation of the segmental structure of the early brain, as well as the development of renal proximal tubules. Weak expression is also detected lung, pancreas, and gastric mucosa. Additionally, it is specifically expressed in the proximal tubule of normal kidneys and in renal cell cancer. Thus, Cadherin-6 is a new prognostic factor for renal cancer. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Cadherin-6 / K-Cadherin / CDH6 protein (TMPY-01050) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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