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Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
还可以产品编号 TMAY-01579
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 是一种 Rabbit 抗体，靶向 Phospho-Met (Tyr1234, 1235)。Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 可用于 WB。
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
还可以产品编号 TMAY-01579
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 是一种 Rabbit 抗体，靶向 Phospho-Met (Tyr1234, 1235)。Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) is a Rabbit antibody targeting Phospho-Met (Tyr1234, 1235). Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9K79 |
| 交叉反应 | Human; Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Rabbit |
| 验证活性 | 1. Western blot analysis of extracts from serum-starved A549, untreated (line A); treated with HGF (50 ng/mL, 5min; +) (line B); treated with HGF and λ-phosphatase (line C) using Phospho-Met(Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from A549, untreated (line A) or treated with HGF (50 ng/mL, 5min; +) (line B), using Phospho-Met (Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution (upper) or Anti-Actin Antibody, Rabbit Monoclonal at 1:50000 dilution (lower). |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-1:5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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