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Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)

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Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
产品编号 TMAY-01579
别名 RCCP2, p-Met (Y1234, 1235), p-Met (Tyr1234, 1235), Phospho-Met (Y1234, 1235), Met (p-Y1234, 1235), Met (p-Tyr1234, 1235), HGFR, DFNB97, DA11, c-Met, AUTS9

Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 是一种 Rabbit 抗体,靶向 Phospho-Met (Tyr1234, 1235)。Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 可用于 WB。

Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
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Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)

Rating icon 还可以
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
产品编号 TMAY-01579 别名 RCCP2, p-Met (Y1234, 1235), p-Met (Tyr1234, 1235), Phospho-Met (Y1234, 1235), Met (p-Y1234, 1235), Met (p-Tyr1234, 1235), HGFR, DFNB97, DA11, c-Met, AUTS9

Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 是一种 Rabbit 抗体,靶向 Phospho-Met (Tyr1234, 1235)。Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) 可用于 WB。

规格价格库存数量
20 μL
¥ 689
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100 μL
¥ 1,979
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产品介绍

生物活性
产品描述
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) is a Rabbit antibody targeting Phospho-Met (Tyr1234, 1235). Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) can be used in WB.
别名RCCP2, p-Met (Y1234, 1235), p-Met (Tyr1234, 1235), Phospho-Met (Y1234, 1235), Met (p-Y1234, 1235), Met (p-Tyr1234, 1235), HGFR, DFNB97, DA11, c-Met, AUTS9
Ig Type
Rabbit IgG
克隆号
9K79
交叉反应
Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Rabbit
验证活性
1. Western blot analysis of extracts from serum-starved A549, untreated (line A); treated with HGF (50 ng/mL, 5min; +) (line B); treated with HGF and λ-phosphatase (line C) using Phospho-Met(Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment)
2. Western blot analysis of extracts from A549, untreated (line A) or treated with HGF (50 ng/mL, 5min; +) (line B), using Phospho-Met (Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution (upper) or Anti-Actin Antibody, Rabbit Monoclonal at 1:50000 dilution (lower).
应用
WB
推荐剂量
WB: 1:1000-1:5000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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