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Anti-CD155/PVR Antibody-PE (9R440) 是一种 PE-conjugated Rabbit 抗体,靶向 CD155/PVR。Anti-CD155/PVR Antibody-PE (9R440) 可用于 FCM。
Anti-CD155/PVR Antibody-PE (9R440) 是一种 PE-conjugated Rabbit 抗体,靶向 CD155/PVR。Anti-CD155/PVR Antibody-PE (9R440) 可用于 FCM。
产品描述 | Anti-CD155/PVR Antibody-PE (9R440) is a PE-conjugated Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody-PE (9R440) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9R440 |
交叉反应 | Mouse |
验证活性 | Analysis of PVR(CD155) expression on Raw264.7 cells. The cells were treated with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 and stained with PE-conjugated anti-Mouse PVR(CD155). The histogram were derived from the gated events based on light scattering characteristics of viable cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD155 / PVR (rM CD155 / PVR; TMPY-00762; NP_081790.1; Met 1-Arg 345) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | PE |
其他可选修饰符 | Unconjugated/APC/PerCP/FITC |
可提供抗体种类 | 5 |
免疫原 | Recombinant Mouse CD155 protein (TMPY-00762) |
抗原种属 | Mouse |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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