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Anti-CRYAB Antibody (6W222)

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Anti-CRYAB Antibody (6W222)
产品编号 TMAC-00155
别名 α-Crystallin B Chain, α(B)-Crystallin, Rosenthal Fiber Component, Renal Carcinoma Antigen NY-REN-27, HspB5, Heat Shock Protein β-5, Heat Shock Protein Beta-5, CRYAB, CRYA2, Alpha-Crystallin B Chain, Alpha(B)-Crystallin

Anti-CRYAB Antibody (6W222) 是一种 Rabbit 抗体,靶向 CRYAB。Anti-CRYAB Antibody (6W222) 可用于 WB,IHC,ICC/IF,IP。

Anti-CRYAB Antibody (6W222)

Anti-CRYAB Antibody (6W222)

Rating icon 还可以
Anti-CRYAB Antibody (6W222)
产品编号 TMAC-00155 别名 α-Crystallin B Chain, α(B)-Crystallin, Rosenthal Fiber Component, Renal Carcinoma Antigen NY-REN-27, HspB5, Heat Shock Protein β-5, Heat Shock Protein Beta-5, CRYAB, CRYA2, Alpha-Crystallin B Chain, Alpha(B)-Crystallin

Anti-CRYAB Antibody (6W222) 是一种 Rabbit 抗体,靶向 CRYAB。Anti-CRYAB Antibody (6W222) 可用于 WB,IHC,ICC/IF,IP。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-CRYAB Antibody (6W222) is a Rabbit antibody targeting CRYAB. Anti-CRYAB Antibody (6W222) can be used in WB,IHC,ICC/IF,IP.
别名α-Crystallin B Chain, α(B)-Crystallin, Rosenthal Fiber Component, Renal Carcinoma Antigen NY-REN-27, HspB5, Heat Shock Protein β-5, Heat Shock Protein Beta-5, CRYAB, CRYA2, Alpha-Crystallin B Chain, Alpha(B)-Crystallin
Ig Type
IgG
交叉反应
Human,Rat
验证活性
1. Western blot analysis of Alpha B Crystallin on human skeleton musle (1) and mouse heart (2) tissues lysate using anti-Alpha B Crystallin antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human embryonic skeletal muscle tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.
4. ICC staining Alpha B Crystallin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into α, β and γ families, and the β- and γ-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, inclu-ding four homologous motifs, a connecting peptide, and N- and C-terminal extensions. α-crystallins consist of three gene products, αA-, αB- and αC-crystallin, which are members of the small heat shock protein family (HSP 20). α-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, α-crystallins do not renature these proteins. Expression of αA-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human αB-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of αB-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 20 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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