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别名 α-Crystallin B Chain, α(B)-Crystallin, Rosenthal Fiber Component, Renal Carcinoma Antigen NY-REN-27, HspB5, Heat Shock Protein β-5, Heat Shock Protein Beta-5, CRYAB, CRYA2, Alpha-Crystallin B Chain, Alpha(B)-Crystallin
Anti-CRYAB Antibody (6W222) 是一种 Rabbit 抗体,靶向 CRYAB。Anti-CRYAB Antibody (6W222) 可用于 ICC/IF,IHC,IP,WB。
Anti-CRYAB Antibody (6W222) 是一种 Rabbit 抗体,靶向 CRYAB。Anti-CRYAB Antibody (6W222) 可用于 ICC/IF,IHC,IP,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-CRYAB Antibody (6W222) is a Rabbit antibody targeting CRYAB. Anti-CRYAB Antibody (6W222) can be used in ICC/IF,IHC,IP,WB. |
| 别名 | α-Crystallin B Chain, α(B)-Crystallin, Rosenthal Fiber Component, Renal Carcinoma Antigen NY-REN-27, HspB5, Heat Shock Protein β-5, Heat Shock Protein Beta-5, CRYAB, CRYA2, Alpha-Crystallin B Chain, Alpha(B)-Crystallin |
| Ig Type | IgG |
| 克隆号 | 6W222 |
| 反应种属 | Human,Rat |
| 验证活性 | 1. Western blot analysis of Alpha B Crystallin on human skeleton musle (1) and mouse heart (2) tissues lysate using anti-Alpha B Crystallin antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human embryonic skeletal muscle tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin. 4. ICC staining Alpha B Crystallin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. ![]() ![]() ![]() ![]() |
| 应用 | ICC/IFIHCIPWB |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into α, β and γ families, and the β- and γ-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, inclu-ding four homologous motifs, a connecting peptide, and N- and C-terminal extensions. α-crystallins consist of three gene products, αA-, αB- and αC-crystallin, which are members of the small heat shock protein family (HSP 20). α-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, α-crystallins do not renature these proteins. Expression of αA-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human αB-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of αB-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 20 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |