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Anti-NFKB1 Antibody (6X277)
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产品编号 TMAC-02821
别名 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Nuclear factor NF-kappa-B p105 subunit, NFKB1, EBP-1, DNA-binding factor KBF1
Anti-NFKB1 Antibody (6X277) 是一种 Mouse 抗体，靶向 NFKB1。Anti-NFKB1 Antibody (6X277) 可用于 WB,ICC,IHC。
Anti-NFKB1 Antibody (6X277)
Anti-NFKB1 Antibody (6X277)
还可以产品编号 TMAC-02821 别名 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Nuclear factor NF-kappa-B p105 subunit, NFKB1, EBP-1, DNA-binding factor KBF1
Anti-NFKB1 Antibody (6X277) 是一种 Mouse 抗体，靶向 NFKB1。Anti-NFKB1 Antibody (6X277) 可用于 WB,ICC,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,990 | 5日内发货 | |
| 100 μL | ¥ 2,985 | 5日内发货 |
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| 产品描述 | Anti-NFKB1 Antibody (6X277) is a Mouse antibody targeting NFKB1. Anti-NFKB1 Antibody (6X277) can be used in WB,ICC,IHC. |
| 别名 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Nuclear factor NF-kappa-B p105 subunit, NFKB1, EBP-1, DNA-binding factor KBF1 |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of NF-κB p105/p50 on MCF-7 cell lysates. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-NF-κB p105/p50 antibody. Counter stained with hematoxylin. 3. ICC staining NF-κB p105/p50 in HepG2 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:200-500; ICC: 1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. |
| 偶联 | Unconjugated |
| 免疫原 | KLH conjugated synthetic peptide: NF-κB p105/p50 |
| Uniprot ID |
| 分子量 | Theoretical: 50 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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