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Anti-IL-18R alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-18R alpha。Anti-IL-18R alpha Polyclonal Antibody 可用于 WB。
Anti-IL-18R alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-18R alpha。Anti-IL-18R alpha Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,975 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-IL-18R alpha Polyclonal Antibody is a Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Polyclonal Antibody can be used in WB. |
别名 | interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a |
Ig Type | IgG |
交叉反应 | Human,Mouse (predicted:Rat,Dog,Pig,Cow) |
验证活性 | Sample: Lane 1: Mouse Blood cell lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-IL-18R alpha (TMAB-00952) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kDa Observed band size: 70 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane; Single-pass type I membrane protein. |
组织特异性 | Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines. |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
浓度 | 1 mg/mL |
研究背景 | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
免疫原 | KLH conjugated synthetic peptide: human IL-18R alpha |
抗原种属 | Human |
基因名称 | IL18R1 |
基因ID | |
蛋白名称 | Interleukin-18 receptor 1 |
Uniprot ID | |
功能 | Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. |
分子量 | Theoretical: 60 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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