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Anti-GPR48 Polyclonal Antibody 3

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货号 TMAB-06719

Anti-GPR48 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 GPR48。Anti-GPR48 Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-GPR48 Polyclonal Antibody 3

Anti-GPR48 Polyclonal Antibody 3

一键复制产品信息
Rating icon 还可以
货号 TMAB-06719

Anti-GPR48 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 GPR48。Anti-GPR48 Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-GPR48 Polyclonal Antibody 3 is a Rabbit antibody targeting GPR48. Anti-GPR48 Polyclonal Antibody 3 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors or heptahelical receptors, interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. LGR4 (leucine-rich repeat-containing G protein-coupled receptor 4), also known as GPR48, is a 951 amino acid multi-pass membrane protein that contains 15 LRR (leucine-rich repeats) and belongs to the GPCR family. Expressed in multiple tissues, including testis, ovary, placenta, stomach, heart, kidney, pancreas and spleen, LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. LGR4 is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LGR4
抗原种属
Human
基因名称
LGR4
基因ID
蛋白名称
Leucine-rich repeat-containing G-protein coupled receptor 4
Uniprot ID
功能
Orphan receptor.
化学信息
分子量Theoretical: 104 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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