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Anti-Nectin-2 Antibody (1C307)
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产品编号 TMAY-03229
别名 PVRR2, PRR2, poliovirus receptor-related 2 (herpesvirus entry mediator B), Nectin-2, HVEB, CD112
Anti-Nectin-2 Antibody (1C307) 是一种 Rabbit 抗体，靶向 Nectin-2。Anti-Nectin-2 Antibody (1C307) 可用于 WB,ELISA,IP。
Anti-Nectin-2 Antibody (1C307)
331 Anti-Nectin-2 Antibody (1C307)
还可以产品编号 TMAY-03229 别名 PVRR2, PRR2, poliovirus receptor-related 2 (herpesvirus entry mediator B), Nectin-2, HVEB, CD112
Anti-Nectin-2 Antibody (1C307) 是一种 Rabbit 抗体，靶向 Nectin-2。Anti-Nectin-2 Antibody (1C307) 可用于 WB,ELISA,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Nectin-2 Antibody (1C307) is a Rabbit antibody targeting Nectin-2. Anti-Nectin-2 Antibody (1C307) can be used in WB,ELISA,IP. |
| 别名 | PVRR2, PRR2, poliovirus receptor-related 2 (herpesvirus entry mediator B), Nectin-2, HVEB, CD112 |
| Ig Type | Rabbit IgG |
| 克隆号 | 1C307 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Anti-mPVRL2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:58 kDa. -Observed band size:58 kDa(We are unsure as to the identity of these extra bands.) 2. Mouse PVRL2 was immunoprecipitated using: -Lane A:0.5 mg Raji Whole Cell Lysate -0.5 µL anti-Mouse PVRL2 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-Mouse PVRL2 rabbit monoclonal antibody, at 1:500 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 58 kDa. -Observed band size: 58 kDa |
| 应用 | WB,ELISA,IP |
| 推荐剂量 | WB: 1:500-1:1000; ELISA: 1:5000-1:10000; IP: 0.2-1 μL/mg of lysate |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PVRL2 extracellular domain (rM PVRL2; TMPY-01150; NP_033016.3; Met 1-Gly 351). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Mouse PVRL2 protein (TMPY-01150) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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