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Anti-IL-17RB Antibody (4T989) 是一种 Mouse 抗体,靶向 IL-17RB。Anti-IL-17RB Antibody (4T989) 可用于 ELISA。
Anti-IL-17RB Antibody (4T989) 是一种 Mouse 抗体,靶向 IL-17RB。Anti-IL-17RB Antibody (4T989) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,689 | 5日内发货 |
产品描述 | Anti-IL-17RB Antibody (4T989) is a Mouse antibody targeting IL-17RB. Anti-IL-17RB Antibody (4T989) can be used in ELISA. |
别名 | interleukin 17 receptor B |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 4T989 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17BR / IL17RB / IL-17 Receptor B (rh IL17BR / IL17RB / IL-17 Receptor B; TMPY-04052; NP_061195.2; Met1-Gly289). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation of the Bcl-2. IL17RB may be the only gene expressed in CD4+ T cells whose transcript measurement is correlated with the variation in IgE level in asthmatics. Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL17BR / IL17RB / IL-17 Receptor B Protein (TMPY-04052) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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