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Granzyme B/GZMB Protein, Mouse, Recombinant (His)

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Granzyme B/GZMB Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00770

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

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产品编号 TMPJ-00770

规格	价格	库存
5 μg	¥ 693	In stock
10 μg	¥ 1,170	In stock
20 μg	¥ 1,860	5日内发货
50 μg	¥ 3,470	5日内发货
100 μg	¥ 4,930	5日内发货
200 μg	¥ 7,350	5日内发货
500 μg	¥ 12,100	5日内发货
1 mg	¥ 18,900	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
种属	Mouse
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	P04187
别名	H),Gzmb,Granzyme B(G,Fragmentin-2,Cytotoxic cell protease 1,CTLA-1,Ctla1,CCP1
氨基酸序列	Gly19-Ser247
蛋白构建	Gly19-Ser247
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	35 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.