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Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00770
别名: Gzmb, Cytotoxic cell protease 1, Fragmentin-2, CTLA-1, Granzyme B(G, H), Ctla1, CCP1

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

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Granzyme B/GZMB Protein, Mouse, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: Granzyme B/GZMB Protein, Mouse, Recombinant (His) (TMPJ-00770)
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产品性质
产品描述 Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
种属 Mouse
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 P04187
别名 Gzmb, Cytotoxic cell protease 1, Fragmentin-2, CTLA-1, Granzyme B(G, H), Ctla1, CCP1
氨基酸序列 Gly19-Ser247
蛋白构建 Gly19-Ser247
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 35 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

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Keywords

Granzyme B/GZMB Protein, Mouse, Recombinant (His) Gzmb CTLA 1 Cytotoxic cell protease 1 CCP 1 CCP-1 Fragmentin-2 CTLA-1 Granzyme B(G H) Ctla1 CCP1 recombinant recombinant-proteins proteins protein

 

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