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Granzyme B/GZMB Protein, Mouse, Recombinant (His)

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SPR兼容缓冲液
货号 TMPJ-00770

别名 H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Granzyme B/GZMB Protein, Mouse, Recombinant (His)
其他形式的 “Granzyme B/GZMB Protein, Mouse, Recombinant (His)”:

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPJ-00770 别名 H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

规格价格库存数量
5 μg
¥ 693
现货
10 μg
¥ 1,170
现货
20 μg
¥ 1,860
5日内发货
50 μg
¥ 3,470
5日内发货
100 μg
¥ 4,930
5日内发货
200 μg
¥ 7,350
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 18,900
5日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
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产品介绍


生物活性
产品描述
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
种属
Mouse
表达系统
HEK293 Cells
标签C-6xHis
蛋白编号P04187
氨基酸序列Gly19-Ser247
蛋白构建Gly19-Ser247
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
别名H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量35 KDa (reducing condition)
颜色Transparent
物理性状Liquid
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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