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Anti-SULT1A1 Antibody (3U284)
还可以产品编号 TMAY-01967
Anti-SULT1A1 Antibody (3U284) 是一种 Rabbit 抗体，靶向 SULT1A1。Anti-SULT1A1 Antibody (3U284) 可用于 IHC-P,ICC/IF。
Anti-SULT1A1 Antibody (3U284)
Anti-SULT1A1 Antibody (3U284)
还可以产品编号 TMAY-01967
Anti-SULT1A1 Antibody (3U284) 是一种 Rabbit 抗体，靶向 SULT1A1。Anti-SULT1A1 Antibody (3U284) 可用于 IHC-P,ICC/IF。
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抗原信息
| 产品描述 | Anti-SULT1A1 Antibody (3U284) is a Rabbit antibody targeting SULT1A1. Anti-SULT1A1 Antibody (3U284) can be used in IHC-P,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3U284 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human SULT1A1 in human cirrhosis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SULT1A1 in human brain with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of SULT1A1 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Y SULT1A1 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| 应用 | IHC-P,ICC/IF |
| 推荐剂量 | IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SULT1A1 (rh SULT1A1; TMPY-02062; P50225-1; Glu2-Leu295). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Particularly SULT1A1 (Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), a member of the sulfotransferase 1 subfamily, which is a major pathway for drug metabolism in humans. Humans have at least 10 functional SULT genes. There has been an explosion in information on sulfotransferase polymorphisms and their functional consequences. An Arg213His polymorphism in SULT1A1 has a strong influence on the level of enzyme protein and activity in platelets, which have been widely used for phenotyping. Statistically significant associations were observed between the SULT1A1 genotype (Arg213His) and age, obesity and certain neoplasias (mammary, pulmonary, esophageal and urothelial cancer). Furthermore, the polymorphism of the SULT1A1 may be closely associated with breast cancer. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SULT1A1 protein (TMPY-02062) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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