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Anti-ATG4A Antibody (2N859)

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货号 TMAB-02919

Anti-ATG4A Antibody (2N859) 是一种 Rabbit 抗体，靶向 ATG4A。Anti-ATG4A Antibody (2N859) 可用于 WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM。

Anti-ATG4A Antibody (2N859)

Anti-ATG4A Antibody (2N859)

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Rating icon 还可以
货号 TMAB-02919

Anti-ATG4A Antibody (2N859) 是一种 Rabbit 抗体，靶向 ATG4A。Anti-ATG4A Antibody (2N859) 可用于 WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ATG4A Antibody (2N859) is a Rabbit antibody targeting ATG4A. Anti-ATG4A Antibody (2N859) can be used in WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM.
Ig Type
IgG
克隆号
2N859
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIPIFICC/IFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IP: 1:20-50; IF: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (Probable).
组织特异性Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine.
抗原信息
免疫原
A synthesized peptide: human Cysteine protease ATG4A
抗原种属
Human
基因名称
ATG4A
基因ID
115201
蛋白名称
Cysteine protease ATG4A
Uniprot ID
Q8WYN0
功能
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
化学信息
分子量Theoretical: 45 kDa. Actual: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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