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Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
还可以产品编号 TMAY-01376
Anti-Phospho-mTOR (Ser2448) Antibody (2R744) 是一种 Rabbit 抗体，靶向 Phospho-mTOR (Ser2448)。Anti-Phospho-mTOR (Ser2448) Antibody (2R744) 可用于 WB。
Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
还可以产品编号 TMAY-01376
Anti-Phospho-mTOR (Ser2448) Antibody (2R744) 是一种 Rabbit 抗体，靶向 Phospho-mTOR (Ser2448)。Anti-Phospho-mTOR (Ser2448) Antibody (2R744) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-mTOR (Ser2448) Antibody (2R744) is a Rabbit antibody targeting Phospho-mTOR (Ser2448). Anti-Phospho-mTOR (Ser2448) Antibody (2R744) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2R744 |
| 交叉反应 | Human; Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus; Predicted to React with:Phospho-mTOR (Ser2448); Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus |
| 验证活性 | Western blot analysis of extracts from serum-starved HEK-293 treated without peptide (line A) or antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-mTOR (Ser2448) rabbit monoclonal Antibody at 1:5000 dilution. |
| 应用 | WB |
| 推荐剂量 | WB: 1:2000-1:20000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | MTOR (Mechanistic Target Of Rapamycin Kinase) is a Protein Coding gene. The protein encoded by the MTOR gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. MTOR is a central regulator of cellular metabolism, growth, and survival in response to hormones, growth factors, nutrients, energy, and stress signals. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. MTOR is broadly expressed in the testis, brain, and other tissues. Diseases associated with MTOR include Smith-Kingsmore Syndrome and Focal Cortical Dysplasia, Type Ii. The ANGPTL7 gene is located in an intron of this gene.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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