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Anti-Azurocidin/CAP37 Antibody (9O126) 是一种 Rabbit 抗体,靶向 Azurocidin/CAP37。Anti-Azurocidin/CAP37 Antibody (9O126) 可用于 ELISA。
Anti-Azurocidin/CAP37 Antibody (9O126) 是一种 Rabbit 抗体,靶向 Azurocidin/CAP37。Anti-Azurocidin/CAP37 Antibody (9O126) 可用于 ELISA。
产品描述 | Anti-Azurocidin/CAP37 Antibody (9O126) is a Rabbit antibody targeting Azurocidin/CAP37. Anti-Azurocidin/CAP37 Antibody (9O126) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9O126 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Azurocidin / CAP37 / AZU1 (rh Azurocidin / CAP37 / AZU1; TMPY-00672; NP_001691.1; Met1-Pro250). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Neutrophils arriving first at sites of inflammation release Azurocidin, which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. It thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Azurocidin / CAP37 / AZU1 Protein (TMPY-00672) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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