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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-OLIG1 Antibody (5J665)

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货号 TMAB-09766

Anti-OLIG1 Antibody (5J665) 是一种 Rabbit 抗体，靶向 OLIG1。Anti-OLIG1 Antibody (5J665) 可用于 WB。

Anti-OLIG1 Antibody (5J665)

Anti-OLIG1 Antibody (5J665)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09766

Anti-OLIG1 Antibody (5J665) 是一种 Rabbit 抗体，靶向 OLIG1。Anti-OLIG1 Antibody (5J665) 可用于 WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-OLIG1 Antibody (5J665) is a Rabbit antibody targeting OLIG1. Anti-OLIG1 Antibody (5J665) can be used in WB.
Ig Type
IgG
克隆号
5J665
反应种属
Human (predicted:Rat,Mouse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
抗原信息
免疫原
A synthesized peptide: human Oligo1
抗原种属
Human
基因名称
OLIG1
基因ID
116448
蛋白名称
Oligodendrocyte transcription factor 1
Uniprot ID
Q8TAK6
功能
romotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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