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Anti-EPCR Antibody-FITC (9U126)
还可以产品编号 TMAY-03487F
Anti-EPCR Antibody-FITC (9U126) 是一种 FITC-conjugated Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody-FITC (9U126) 可用于 FCM。
Anti-EPCR Antibody-FITC (9U126)
Anti-EPCR Antibody-FITC (9U126)
还可以产品编号 TMAY-03487F
Anti-EPCR Antibody-FITC (9U126) 是一种 FITC-conjugated Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody-FITC (9U126) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-EPCR Antibody-FITC (9U126) is a FITC-conjugated Rabbit antibody targeting EPCR. Anti-EPCR Antibody-FITC (9U126) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9U126 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse PROCR(CD201) expression on bEnd.3 cells. Cells were stained with FITC-conjugated anti-Mouse PROCR(CD201). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Epcr/PROCR (rM Epcr/PROCR; TMPY-02487; Q64695; Met1-Ser214) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Mouse Epcr/PROCR Protein (TMPY-02487) |
| 抗原种属 | Mouse |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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