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Anti-ABCB1 Antibody (1E952)
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产品编号 TMAC-02928
别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Anti-ABCB1 Antibody (1E952) 是一种 Rabbit 抗体，靶向 ABCB1。Anti-ABCB1 Antibody (1E952) 可用于 WB,IHC。
Anti-ABCB1 Antibody (1E952)
Anti-ABCB1 Antibody (1E952)
还可以产品编号 TMAC-02928 别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Anti-ABCB1 Antibody (1E952) 是一种 Rabbit 抗体，靶向 ABCB1。Anti-ABCB1 Antibody (1E952) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-ABCB1 Antibody (1E952) is a Rabbit antibody targeting ABCB1. Anti-ABCB1 Antibody (1E952) can be used in WB,IHC. |
| 别名 | PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Cells selected for resistance to a single cytotoxic drug may become cross-resistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). The MDR proteins (Mdrs) are members of a highly conserved superfamily of ATP-binding cassette transport proteins. Mdr functions as an energy-dependent efflux pump for structurally diverse agents ranging from ions to peptides. It is implicated in the development of the multiple drug resistance observed in human cancer cells following prolonged chemotherapy. The classic form of MDR is associated with an increase in the Mdr protein, but not all cases of MDR can be attributed to a rise in Mdr levels. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. In the human population, there are 15 polymorphisms in the Mdr-1 gene. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 180 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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